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PSP® in cosmetic research |
Through years of research, physicians discovered fetal skin has a unique ability to heal wounds without scarring. Inspired by this, medical researchers at the University Hospital of Lausanne, Switzerland created a biotechnology process to extract the rich proteins responsible for scarless wound healing from cultured fetal skin cells. A small biopsy of fetal skin was donated following a one-time medical termination and a dedicated cell bank was established for developing new skin treatments. Originally established for wound healing and burn treatments, today this same cell bank also provides a lasting supply of cells for producing Neocutis’ proprietary skin care ingredient Processed Skin Cell Proteins (PSP®). No additional fetal biopsies will ever be required. |
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| The story behind PSP® … |
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Investigating an optimal follow-up regimen for treating burn and ulcer patients with a three-dimensional skin allograft comprising cultured fetal skin cells seeded onto a collagen matrix [23, 24], the research team at University Hospital of Lausanne developed a cream containing the cell lysate of the same cultured fetal skin cells as used for the graft preparation. The cell lysate was later called Processed Skin Cell Proteins (PSP®).
As an example, the right Figure illustrates the use of PSP® containing cream to improve texture and appearance of the skin in a woman 65 years of age with a healed leg ulcer. The figure shows the leg after grafting was complete and the wound closed (upper picture), and after the PSP® cream was applied daily for approximately six months (lower picture).
Together with the help of a compression bandage, the follow-up regimen aimed to improve texture and appearance of skin once the wound was closed and had completely healed. |
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