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BLANCHE Skin Lightening Cream

Skin lightening cream with MELAPLEX® technology helps visibly lighten skin discoloration in as little as 4 weeks.*


BLANCHE Skin lightening Cream (Hydroquinone USP, 4%) Rx Only Formulated with Melaplex®

MELAPLEX®, an exclusive skin brightening complex is combined with Hydroquinone 4%, the #1 physician choice for topical skin lightening, to help visibly diminish the appearance of dark spots and pigmentation. Blanche takes skin lightening to a bright new level!

Blanche Skin Lightening Cream (Hydroquinone USP, 4%) with MELAPLEX® helps to*:

  • Visibly lighten dark (brownish) skin discolorations.
  • Brighten and restore the look of skin tone and clarity for a more even complexion.
  • Provide light hydration to counteract dryness.
  • Formulated with anti-oxidants to help maintain the appearance of youthful looking skin.


All skin types: Non-comedogenic • Dermatologist tested • Free of color additives and fragrances • Steroid-free.


Use nightly only. Use JOURNÉE Bio-restorative Day Cream with PSP® Broad-Spectrum SPF 30 for optimal results during the day. For more information about BLANCHE® Skin Lightening Cream, see full Prescribing Information.





Active Ingredients: Hydroquinone USP, 4%

Inactive Ingredients: Purified Water, Glyceryl Stearate, Cetearyl Alcohol, Sodium Glycerophosphate, Diisopropyl Adipate, Caprylyl Methicone, Glycerin, Ceteareth-20, Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer, Isohexadecane, Leucine, Dimethicone, Simmondsia Chinensis (Jojoba) Seed Oil, Butyrospermum Parkii (Shea Butter), Citric Acid, Phenoxyethanol, Undeclyenoyl Phenylalanine, Phenylethyl Resorcinol, Aminopropyl Ascorbyl Phosphate, Sodium Metabisulfate, Polysorbate 60, Xanthan Gum, Chlorphenesin, Tocopheryl Acetate, Disodium EDTA.


BLANCHE® contains sodium metabisulfite, a sulfite that may cause serious allergic-type reactions (e.g., hives, itching, wheezing, anaphylaxis, severe asthma attack) in susceptible persons.

Important safety information

BLANCHE® Skin Lightening Cream (hydroquinone 4%) is indicated for the short-term and intermittent long-term treatment of dark discolorations in the skin. In order to improve outcome, BLANCHE® Skin Lightening Cream should be used with measures for sun exposure limitations, like using sunscreen of SPF 30 or higher. Tell your doctor if you are allergic to sulfites since BLANCHE® Skin Lightening Cream contains sulfites which may cause severe, life-threatening allergic reactions. BLANCHE® Skin Lightening Cream contains hydroquinone. Hydroquinone may rarely cause a gradual blue-black darkening of the skin. In addition, burning, itching, dryness, redness, and peeling may occur. There is inadequate evidence in humans for the carcinogenicity of hydroquinone and limited evidence in experimental animals. You should not use BLANCHE® Skin Lightening Cream if you are pregnant, nursing or trying to become pregnant. Exposure to sunlight, sunlamps, or UV light and extreme heat or cold should be limited. BLANCHE® Skin Lightening Cream should not be used with irritating products such as abrasive cleansers, scrubs, skin-peeling agents, or with light and laser procedures. The use of BLANCHE® Skin Lightening Cream should be limited to once daily at night to relatively small areas of the body such as the face, hands and décolleté. BLANCHE® Skin Lightening Cream is for external use only; it is not for ophthalmic use. Keep BLANCHE® Skin Lightening Cream out of reach of children.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.

*Individual results will vary.

Click here to view the BLANCHE Material Safety Data Sheet (MSDS)


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