Key Benefits
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Preserve with Growth Factors
- Renews the feel of skin suppleness and softness
- Helps smooth the appearance of lines and wrinkles with 0.05% Growth Factors
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Intensively Hydrate
- Promotes suppleness and smoothness with moisturizing lipids combined with hydrating Glycerin
- Nourishing oils moisturize skin to promote a more refined tone and texture
- Wild Yam Root Extract helps counteract dryness and textural skin changes associated with climate and/or hormonal shifts
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Replenish
- Helps replenish skin after cosmetic or dermatological procedures
- Can be used as adjunctive skincare with topical prescription medications
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A richer, more emollient version of BIO CREAM
Application
- Apply in the morning and/or evening to the face, neck and décolleté, or as directed by your skincare professional.
- If used during the day, add a broad-spectrum sunscreen like RéACTIVE®+*, JOURNÉE or MICRO DAY®.
*If using as part of an aftercare ritual, avoid anti-oxidant products like RéACTIVE+ and retinol products like NOUVELLE+ until skin has fully healed.
Daily Ritual
- Begin with a daily cleanser.
- Follow up with targeted products such as retinols (NOUVELLE+®*) or eye creams (LUMIÈRE® RICHE).
- Apply BIO CREAM RICHE to replenish and soothe skin.
Demonstrated Benefits Powered by NEOCUTIS Growth Factors


Unretouched photos of actual study subjects. Results based on a study of 18 subjects who applied BIO CREAM twice daily for two months. Results may vary. Date on file; Merz North America, Inc., Raleigh, NC. Photos courtesy of Michael H. Gold, M.D. Tennessee Clinical Research.
Key Ingredients
Growth Factors (anti-aging)
Petrolatum (moisturizing)
Wild Yam Root Extract (skin-conditioning)
Glycerin (moisture-infusing)
Wheat Germ Oil (moisturizing)
Borage Seed Oil (moisturizing)