Key Benefits
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Preserve with growth factors
- Formulated with growth factors to help reduce the appearance of fine lines and wrinkles
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Hydrate
- Provides lasting hydration and moisture retention with Sodium Hyaluronate (SH) and Glycerin
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Defend
- Fights against daily environmental stressors with an intensive anti-oxidant blend of polyphenol-rich Green Tea Extract, stabilized Vitamins C and E, and Melanin
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Protect
- Provides broad-spectrum UVA/UVB sun protection with a non-whitening blend of Octinoxate and micro-fine Zinc Oxide
- Fast-absorbing, non-greasy formula blends flawlessly into skin for lightweight sun protection
Application
- Apply in the morning and/or evening to the face, neck and décolleté, or as directed by your skincare professional.
- For use as a sunscreen, apply generously 15 minutes before sun exposure and reapply every 2 hours.
- Pair with a water-resistant sunscreen if swimming or sweating.
For external use only. Avoid contact with eyes. If contact with eyes occurs, rinse eyes thoroughly with water. Discontinue use if signs of irritation or rash appear. Keep out of reach of children.
Daily Ritual
- Begin with a daily cleanser.
- Follow up with targeted products such as eye creams (LUMIÈRE®) or neck creams (MICRO FIRM™).
- Apply JOURNÉE for anti-aging sun protection and hydration.
Demonstrated Benefits Powered by NEOCUTIS Growth Factors


Unretouched photos of actual study subjects. Results based on a study of 11 subjects who applied BIO CREAM twice daily for six months. Results may vary. Date on file; Merz North America, Inc., Raleigh, NC. Photos courtesy of David J. Goldberg, M.D., Skin Laser and Surgery Specialists of New York and New Jersey.
Key Ingredients
Growth factors (anti-aging)
Octinoxate 7.5% and Zinc Oxide 7.3% (UVA/UVB broad-spectrum sun protection)
Sodium Hyaluronate (hydrating)
Glycerin (moisture-infusing)
Vitamins C and E and Melanin (synergistic anti-oxidant care)